Sooo many options for pizza. Lou Malnati's, Pizzaria Uno, and Gino's East are amongst the 3 usual/standard recommended deep dish places. The latter two arent too far from your hotel. Pizzaria Due was always busy anytime I was near there but it doesn't look like they're open right now(?). There are plenty of smaller pizza places around your hotel to try as well. Or say 'f' it and go grab some Portillo's.
As for crime, just stay out of the South and West sides. When you hear about Chicago on the news, it's mostly due to those areas. Mostly.
If you want a self guided tour spanning the spectrum of the city, just take a drive up/down Halsted (just don't start too far South).
